HPMC: Forcoat C

 

System ForCoat C

It is the newest invention created as a result of long-term research work in case of universal shell enabling even more efficient and shorter coating. ForCoat C coats are very flexible and mechanically durable due to usage of properly micrionized microcrystalline cellulose which gives the coat micro- reinforcement. High content of filming polymer prevents coat attrition during the coating process. System throughout its rheological qualities and large content of polymer allows to shorten the time of coating process, which provides very great savings in man-hour.

The coating rate depends on the size of the batch and the type of used coating machine. During technological trials using basic ForCoat C shell Yellow Y200 the expected 3% increase was achieved, for example:

  • in 150 minutes for deposit of 500 kg of tablets in coating machine Glatt GC Smart
  • in 160 minutes for deposit of 200 kg with full barrel in machine IMA GS
  • 30 minutes in machine ZMR with perforated barrel for batch of 200 kg of tablets.


Pic.1 Comparison of coating times to achieve 3% weight gain in three coating devices. Used coat: Forcoat Yellow Y200.

Important advantage of ForCoat C system for all types of tested machines is pressure reduction in peristaltic pumps of particular machines. It favors to achieve bigger sprays in unit of time and simultaneously it reduces the effect of tablets sticking together. It favors to achieve higher speeds of coating.

System’s components strengthens the core of tablets already at an preliminary coating stage. Thanks to that using the higher rotation of the barrel is possible. It favors the better distribution of shells growth and prevents flooding the deposit.

ForCoat C system allows to successfully coat the highly abrasive tablets with one condition – to start the coating process with low temperature of the deposit, about 30˚C. This conditions should be preserved for abrasive tablets to achieve 1% weight gain of the tablets. High polymer content in system stabilizes the tablets surface on this level, that after achieving 1% of tablets weight gain the coating process could be carry on as standard.

System is based on composition:

Hypromellose (HPMC) E 464
Polydextrose or Sucrose E 1200
Titanium dioxide E 171
Polyethylene glycol E 1521
Microcrystalline cellulose E 460
Talc E 553b
Tween E 433
Pigment or isoflavonoide

 

This system is available in various colors based on soluble dyes or dyes lakes admitted to use in food industry and also according to the patent application in colors based on isoflavonoids.

Using the ForCoat C system brings significant economic benefits resulting from shortening of coating time and allows for efficiency increase during the production of large-scale series. During the production of a few series of same product one after the other, the time is saved by skipping the process of washing pumps and device. ForCoat C lacquer through its thixotropic qualities do not agglomerates in peristaltic pump’s hoses and in dead places of space in spraying system.